In this text I intend to show to what extent a certain epistemological understanding of psychoanalysis (fundamentally Freudian) finds parallels with the so-called liberalization process of epistemological naturalism. My thesis is that the sui generis epistemological modalities created by Freud not only coincide with this process, but to a significant degree were precursors of the methodological and ontological innovations that LN (liberal naturalism) proposes to defend and theorize. I begin by reviewing the process of liberalization of epistemic naturalism, from a predominantly physicalist model to a liberal version that takes into account other parameters and especially the progressive development of the human sciences. In the second part I aim to show that certain methodological modalities of psychoanalysis and the alternative epistemological conceptions that underlie it confirm this process of liberalization, contribute to it, and even, to some extent, were its precursors.