Argumenta – Journal of Analytic Philosophy

Recent human microbiome research has suggested that racial patterns between different groups of people can be understood as variation in how many and which microbes live in and on their bodies. Such racial classifications (from ‘Indigenous’ to ‘Black’ or ‘Caucasian’) are said to be helpful to better grasp microbiome-linked health-disparities (especially in the Global South) and diseases such as obesity and type 2 diabetes. In this paper, we argue that this assumption is illusive. We identify four different scenarios and argumentative patterns in current human microbiome research, which state that…

Recent research shows that the inappropriate use of race and ethnicity in healthcare leads to poor patient outcomes. Contemporaneous work shows that accounting for inequalities caused by discrimination often requires the use of race and ethnicity as variables that are mediated in their effects by discrimination along those dimensions of identity and/or classification. This suggests that the appropriateness of using racial and ethnic group descriptors depends on context. This paper explores some contexts in which the use of racial and ethnic group descriptors may be appropriate, and the limitations thereof.…

Debates over the use of racial categories in medicine have, thus far, been largely focused on cases and considerations occurring in the United States. However, race is used in medical settings in many places outside the US. I argue that the US focus leads to important limitations in our ability to understand and intervene on issues of race in medicine in other areas of the world. I draw on work from metaphysics of race debates to indicate why transnational continuities and discontinuities in race present a problem for US focused…

The application of health recommender systems (HRSs) in the mobile-health (m-health) industry, especially for healthy active aging, has grown exponentially over the past decade. However, no research has been conducted on the ethical implications of HRSs and the ethical principles for their design. This paper aims to fill this gap and claims that an ethically informed re-definition of the AI ethics principle of autonomy is needed to design HRSs that adequately operationalize (that is, respect and promote) individuals’ autonomy over ageing. To achieve this goal, after having clarified the state-of-the-art on…

In the understanding and prediction of a pandemic phenomenon, epidemiology is obviously the dedicated discipline. However, epidemiological models look at what we might call the proximate causes of the pandemic. On the other hand, the ultimate causes, those of an ecological, evolutionary, and socio-economic nature, are often too simplified or reduced to “minor” variables in epidemiological models. In this article, in dealing with a pandemic, we want to support the need to extend the study and design of responses to the ultimate causes and the disciplines that investigate them, with…

As the COVID-19 pandemic has demonstrated, barriers to vaccination uptake are heterogeneous and vary according to the local context. We argue that a more systematic consideration of local social and behavioural mechanisms could improve the development, assessment and refinement of vaccination uptake interventions. The EBM+ approach to evidence appraisal, which is a development of a recent line of work on the epistemology of causality, provides a means to evaluate mechanistic studies and their role in assessing the effectiveness of an intervention. We argue that an EBM+ methodology offers several potential…

Never as with the present pandemics, numbers and the attendant activities of measuring and modelling have taken centre-stage. Yet these numbers, often delivered by academicians and media alike with extraordinary precision, rely on a rich repertoire of assumptions, including forms of bias, that can significantly skew both the numbers per se and the trust we repose in them. We discuss the issue in relation to a particular case relative to the numbers on excess mortality during the first wave of the Covid-19 pandemic in Italy. We conclude with some considerations…

This paper is inspired by a thesis on “immune capital” by Kathryn Olivarius. We suggest that the biological capital, which immunity capital is part of, should be considered as an additional component of the life-course experience of individuals, together with the traditional Bourdieu’s social, economic and cultural capitals that drive their lives. Building upon this concept, we consider the relationships between science, society and policy-making in the course of the pandemic. We suggest that we need to ‘reframe problems so that their ethical dimensions are brought to light’ (Jasanoff), with…

In this paper, I argue that evidence of biological and socio-behavioural mechanisms can contribute to the management of Covid-19. I discuss two examples that show how scientists are using different forms of evidence, among which mechanistic evidence, to answer questions about the efficacy of vaccines against Covid-19 and the effectiveness of vaccination interventions in different contexts. In the first example I claim that, due to the fast pace of the pandemic, mechanistic reasoning and evidence of biological mechanisms play an important role in the study of vaccines’ efficacy and the…

In this paper, we analyse some of the challenges that pharmacovigilance, the science of detecting and assessing possible adverse reactions from medical interventions, is facing during the COVID-19 pandemic. In particular, we consider the issue of increased uncertainty of the evidence and the issue of dealing with an unprecedented amount of data. After presenting the technical advances implemented in response to these two challenges, we offer some conceptual reflections around such practical changes. We argue that the COVID-19 emergency represents a chance to push forward critical thinking in the field…